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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLSCR1
All Species:
27.58
Human Site:
S249
Identified Species:
55.15
UniProt:
O15162
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15162
NP_066928.1
318
35049
S249
D
V
D
F
E
I
K
S
L
D
E
Q
C
V
V
Chimpanzee
Pan troglodytes
XP_001135562
311
34199
S242
D
V
D
F
E
I
K
S
L
D
E
Q
C
V
V
Rhesus Macaque
Macaca mulatta
XP_001111222
318
35056
S249
D
V
D
F
E
I
K
S
L
D
E
Q
C
V
V
Dog
Lupus familis
XP_854267
356
38604
S286
D
V
D
F
E
I
K
S
L
D
E
E
N
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCW2
307
34062
S247
D
I
D
F
E
I
K
S
L
D
E
V
T
R
I
Rat
Rattus norvegicus
P58195
335
36692
S266
D
I
D
F
E
L
K
S
L
D
E
E
S
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520623
294
32532
G231
D
V
D
F
Q
V
K
G
L
D
D
Q
T
V
V
Chicken
Gallus gallus
XP_001231237
305
33647
S235
D
V
N
F
E
V
K
S
L
D
E
V
S
N
V
Frog
Xenopus laevis
Q92125
512
53295
N360
G
I
V
D
E
S
Q
N
V
N
M
Q
Q
A
E
Zebra Danio
Brachydanio rerio
NP_998031
314
34580
G243
D
V
H
F
E
L
K
G
K
D
G
T
G
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648389
416
43675
S347
D
V
E
F
N
V
V
S
L
T
G
E
K
I
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001183154
279
30546
A228
W
T
G
F
I
K
E
A
F
T
D
A
D
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
96.8
72.1
N.A.
66.3
71.9
N.A.
67.6
66
21
55.6
N.A.
44.9
N.A.
N.A.
55.3
Protein Similarity:
100
97.8
99
79.2
N.A.
76.7
80.5
N.A.
77
74.8
31.6
65.4
N.A.
53.6
N.A.
N.A.
66.6
P-Site Identity:
100
100
100
86.6
N.A.
66.6
73.3
N.A.
66.6
66.6
13.3
40
N.A.
33.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
80
93.3
N.A.
86.6
80
46.6
46.6
N.A.
60
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% C
% Asp:
84
0
59
9
0
0
0
0
0
75
17
0
9
0
0
% D
% Glu:
0
0
9
0
75
0
9
0
0
0
59
25
0
0
9
% E
% Phe:
0
0
0
92
0
0
0
0
9
0
0
0
0
0
9
% F
% Gly:
9
0
9
0
0
0
0
17
0
0
17
0
9
0
9
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
0
0
9
42
0
0
0
0
0
0
0
9
9
% I
% Lys:
0
0
0
0
0
9
75
0
9
0
0
0
9
9
0
% K
% Leu:
0
0
0
0
0
17
0
0
75
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
9
0
9
0
0
9
17
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
9
0
9
0
0
0
0
42
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
0
0
0
0
0
9
0
67
0
0
0
0
17
0
0
% S
% Thr:
0
9
0
0
0
0
0
0
0
17
0
9
17
0
0
% T
% Val:
0
67
9
0
0
25
9
0
9
0
0
17
0
50
59
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _